Syllabus

Diagnosing HIV and the Initial Evaluation of HIV-Infected patient

  • Conduct an initial history & physical of a newly diagnosed HIV-infected patient.
  • Stage patients’ HIV disease severity based on both CDC and WHO HIV classifications.

Opportunistic Infections 1: Non-Neuro, non-TB

  • Outline the diagnosis and management of Pneumocystis jirovecii pneumonia, disseminated Mycobacterium avium complex, Candidal esophagitis, and Cytomegalovirus disease in patients with AIDS.
  • Explain the key and expanded role of co-trimoxazole prophylaxis in the resource-limited setting.

Intro to Antiretroviral Therapy

  • Describe the goals of antiretroviral therapy and indications for starting
  • Identify the distinguishing features of each class of antiretrovirals, as well as the pros/cons of different regimens.

Opportunistic Infections 2: TB, Cryptococcus, Toxoplasmosis and Progressive Multifocal Leukoencephalopathy

  • Describe the management of cerebral toxoplasmosis, progressive multifocal leukoencephalopathy, and Cryptococcal meningitis.
  • Explain the interaction between HIV and TB, and the principles of TB treatment in the HIV-infected patient.

HIV-associated Malignancies & Dermatology

  • Identify the key clinical features of the major AIDS-defining malignancies: Kaposi’s sarcoma, Non-Hodgkin’s lymphoma, Primary CNS lymphoma.
  • Recognize and recall common themes in HIV-related skin disease.

Antiretrovirals: Adverse Effects, Drug Resistance, and Drug Interactions

  • Describe the adverse effects of antiretroviral agents – both common and severe.
  • Outline the indications for HIV resistance testing as well as the approach in resource-limited settings when such testing is not available.

Management of Sexually Transmitted Infections in HIV-infected Patients

  • Identify the most common STI syndromes.
  • Differentiate between the syndromic versus etiologic approach to management of STIs in HIV-infected patients.

Pediatric HIV

  • Contrast the natural history and manifestations of HIV in infants and children from that of adults.
  • Describe the unique challenges in diagnosis and management in pediatric HIV, particularly from global perspective.

Post-exposure Prophylaxis for HIV and Preventive Care

  • Outline the strategies to reduce secondary HIV transmission, starting with the infected patient.
  • Recognize the indications for post-exposure prophylaxis for both occupational and sexual HIV exposures.

HIV Vertical Transmission and Pregnancy

  • Discuss the risk factors for mother-to-child HIV transmission (MTCT), as well as the interventions to prevent MTCT in both US and resource-limited settings.